Illumina plans to lay off 58 employees, according to documents filed with the State of California Employment Development Department.

According to California's Worker Adjustment and Retraining Notification (WARN) report, earlier this month the state received notice that Illumina will lay off 42 employees in San Diego and 16 employees in Foster City, effective Nov. 5.

The firm is headquartered in San Diego and uses its Foster City campus to further its presence in the Bay Area.

Illumina disclosed last month that it was undergoing an organizational restructuring, along with the January 2020 departure of Garret Hampton, senior vice president of clinical genomics. Whether the layoffs are related to the organizational restructuring is unclear. Illumina did not immediately respond to a request for comment.

The layoffs follow a recent stretch of bad news for Illumina. In July, the company projected it would miss its second quarter revenue estimates by more than $50 million and lowered its full-year revenue guidance. Last month, the firm reported second quarter revenues of $838 million, short of the Wall Street estimate of $888 million, attributing the revenue shortfall to slowness in population genomics initiatives and weakness in the direct-to-consumer market.

And in May, Illumina-backed startup Helix reduced its workforce; Illumina later disclosed that it had deconsolidated its ties to Helix.