Original from: life sciences review
Biotech firms experienced a banner year in 2020.The COVID-19 pandemic highlighted the value of innovative medical solutions, leading to new opportunities for researchproduct approvaland funding
The list of Top 10 Biotech Startups Companies-2022
1. AtlasXomics
Commercializing a novel spatial biology tools platform-Deterministic Barcoding in Tissue for spatial-omics sequencing(DBiT-se)-that provides researchers and clinicians with unprecedented multi-omics maps of gene expression of tissue sections
By pinpointing specific changes in the varying cell groups of the central nervous system in neuro patients,DBiT-seq can help researchers better understand mechanisms of action and identify the safest and most effective approaches to drug discovery
-Ken Wang,CEO
2. ConcarloTherapeutics
Concarlo's innovative and patente d lpYa novel therapeutic peptide will be the first to address CDK2 resistance the first to target p27, and the first to inhibit both CDK4 and CDK2 at the same timeConcarlo targets a specific cellulan pathway to kill tumor cells rather t han iust slowing their proliferation.The company relies on the role of p27Kip1 - a vital "ON-OFF" switch that regulat es the activities of major cancer-related proteinsCDKCDK6and CDK2.
Concarlo Therapeutics is a woman-founded and run organization that is working towara revolutior hizing the metastatic breast cancer field"says DrStacy Blainthe companys Co-founder&ChiefScientific Officer
3. DelNova
In 2016, Mary Gardner, the Founder and CEO,laid the foundation of DelNova.It is the only company in the industry that is developing a feasible solution,ReViVox™,to address botulinum toxin type A complications following aesthetic and medical neurotoxin theranies Unlike others in the industry who have tried to resolve this issue bw focusing on the toxin,DelNova addresses these complications'outside of the neuron¡¯Its novel solution, ReViVox acts as the perfect rescue product for all these complications without changing the toxin.DelNova is currently in the preclinical stage and is working toward collecting clinical data to validate the initial success of ReViVox. The company has already conducted a preliminarynon-clinical proof of conceptcollaborating with CRO partners to generate positive proof-of-concept data.
With Our Robust Solutions,We Offer Comfort And Assurance To Both Patients And Practitioners
-Mary Gardner, Founder and CEO
4. Gain Therapeutics
Gain Therapeutics is a preclinic cal biotechnology company focused on developing new medicines for protein misfolding diseases.
Gain The erapeutics Is The First Company To Successfully Combine Advance ements In Computational BiologyStructural Biology,And Superco mputers To Develop Drugs
-Eric Richr man,cEO
5. Gator Bio
Gator Bio assists the R&D of th herapeutic drugs with a best-in-class platform-Biolayer Interferometry(BLl)-that detects biomolecular interactions for rapid auantitation.kinetic measurements. epitope binningand small molecule analysis. The BLI is a brilliant combination of engineering and sciences that results in revolutionaryanalytical technologies with superior perfor mance and convenience at a fraction of the cost of traditional products.
The Gat or Prime and the Gator Plus platforms comprehensively meet the needs of all small a and medium biotech companies who are developing different therapeutics or biologics
¡ª¡ªHONG TAN FOUNDER AND CEO
6. lbex Biosciences
Developing gene therapies, a ntibodies, and regenerative platforms for treatment of cancer malaria and other diseases.
We are taking high-risk,high-reward approaches that are demonstrating activity agai inst cancer and other urgent conditions
-Norman LaicTOVidal de la CruzCSO&Co-CEOA.Murat CrociCo- Founder &Co-CEO,Saule Dairabayeva,Markets Manager,Michael J. Karlin,Co-Founder &CBO-ShawnladonatoPh hD,CEO
8. LEUKOCARE
Leukocare is a leading provider o f bioinformatics based drug product formulation and development of technologies for the biological functionalizatic on of medical devices, as well as the stabilization and protection of proteins. Leukocare stepped into the bioph harmaceutical sector as a product development company almost 20 years ago;. It pioneered the development of a coating for filter membrane,employing an antibody to reduce the activity of neutrophil granulocytes.
We are h ighly specialized in stabilizing all kinds ofbiological molecules And we have a very stror ng bioinformatics based approach which we apply to different project resulting in an optimized formulation using less drug substance in less times
-MICHAELS SCHOLL,CEO
9. MAIA Biotechnology
MAIA Biotechnology is a targe ted therapy immune-oncology company focused on developing and commercializing first-in-class drugs with novel mechanisms of action.
We envision testing THIO against as many tumor types and checkpoint com abinations as possible to realize its full potential to benefit a large population of pati ients
-VladVitoc,Founder and CEO
10. MOBILion SYSTEMSINC
MOBILion Systemsstructures for lossless ion manipulation(SLIM)technology provides unprecedented capability to separate clinically relevant molecules for MS analysis It helps researchers drastically improve metabolic disease drug,and biomarker discoverypaving th he way for earlier disease detection more accurate diagnostics and reduced healthcare costs.Moreimportantl ySLIM provides a very long, 13 meter path length to allow for maximum ion separation. As a resultresearchers ca n use the arrival time as a fourth dimension of separation to accurately resolve isomers.
SLIM delivers cr itical quality attributes through high resolution reproducibility, and speed to advance biotherapeutics
-Julie SperrySenior Vice President Biopharma Business
Source: Top 10 Biotech Startups Companies-2022